Prevent Cancer Foundation Blog

Researcher Q & A with Lauren Trepanier, DVM, PhD

Posted by PCF Admin on December 20th, 2011 | No Comments »
Sarah AbouElSeoud

Research - [caption id="attachment_6109" align="alignright" width="166" caption="Photo Credit: University of Wisconsin-Madison"][/caption] The Foundation is proud to highlight the breast cancer research of Lauren Trepanier, DVM, PhD, a professor at the University of Wisconsin-Madison’s School of Veterinary Medicine. Dr. Trepanier received a two-year grant from the Foundation in spring 2008 to examine whether specific enzymes present in the human breast are associated with breast cancer risk. What led you to the field of breast cancer research? I began my career by studying adverse drug reactions, in particular sulfonamide hypersensitivity (sulfa drug allergy). We wanted to understand why these drug reactions occur in certain patients, so we were studying the pathways that the body uses to detoxify, or neutralize, these drugs. We found that humans use a key enzyme pathway (cytochrome b5 and its reductase) to detoxify sulfonamide drugs. We also found that we use this same pathway to neutralize certain environmental carcinogens that have been associated with breast and other cancers. Tell us about your research examining the role of two enzymes, b5R and cyt b5, in eliminating cancer-causing metabolites in the breast and whether individual differences in these enzymes are associated with breast cancer risk. The enzymes b5 (cytochrome b5) and b5R (cytochrome b5 reductase) neutralize cancer-causing ...

Cancer Queens Use “Edutainment” to Promote Screening and Awareness

Posted by Sheila Bates, MSSW, Manager, Community Outreach, Vanderbilt-Ingram Cancer Center on December 15th, 2011 | No Comments »
Bates Cancer Queen 10-21-08

Community Outreach - Envision a group of women donning feather boas and rhinestone tiaras, dancing to the sound of “The Loco-motion” while singing the lyrics, “Every woman needs this lifesavin’ test now. Come on baby, go and get your Pap smear.” These 10 lovely ladies are a part of Vanderbilt-Ingram Cancer Center’s Cancer Queens! A Cancer Prevention Musical Revue! This traveling troupe of professional health educators volunteer to perform a 45-minute, live show featuring skits and song and dance ...

Aerial Silks — Fitness and Fun at the Big Top

Posted by Liona Chan, Communications Associate on December 14th, 2011 | No Comments »
Liona

Exercise Daily - During the holidays, cold weather and decadent food can make it challenging to stay active throughout the seemingly never-ending winter season. This year, ditch that boring gym workout for something a little different. [caption id="attachment_5882" align="alignright" width="225" caption="Christina Kaoh"][/caption] You might have seen it at Cirque du Soleil or during Pink’s high flying performance at last year’s Grammy awards, and it’s called aerial silks. The performances are literally dances in the air complete with extreme poses and ...

US Senate Commemorates National Cancer Act 40th Anniversary

Posted by Lisa Hughes, Senior Director, Policy & Advocacy on | No Comments »
LisaHughes

Advocacy - December 2011 marks a milestone in the Federal commitment to the war on cancer. Forty years ago, the US Congress passed, and President Richard Nixon signed, the National Cancer Act of 1971, a bill which expanded our country’s national cancer program and gave the National Cancer Institute unprecedented authority and resources to begin a comprehensive approach to understanding and developing more effective tools to prevent and treat cancer. Today, several members of the United States Senate, ...